Oregon grape is an evergreen shrub which grows throughout the American northwest. My knowledge of grapes has been confined to the health benefits and taste of green vs. red grapes. Oregon grape (Mahonia aquafolium) is famous as a powerful antimicrobial herb. Oregon Grape root is a remarkable herb for a variety of reason – not the least of which is affordability and availability as many of its high berberine plant cousins are reaching critical levels of over harvesting. Oregon grape, which is easily cultivated, has been suggested as a substitute for goldenseal, which is often difficult to find, and has been listed as endangered. Considered an AMPK activator, berberine may also help support healthy metabolic support in relation to fatty acids, glucose storage, and ketones. Oregon Grape contains alkaloids (especially berberine and oxycanthine) and other substances. Follow her blog at Herbalism Manifesto for commentary on herbs, parenting, nutrition and a whole lot more. It interferes with the metabolism of the bacteria’s ability to produce protein, DNA and other cellular functions. Pinning you Hub! Holly flowers are white and their berries are red. Oregon grape contains berberine, a powerful plant compound that may relieve many health conditions. :). Berberine is a natural compound found in plants of the genus Berberis, including goldenseal and Oregon grape. Identification is important whenever a person forages for food in the wild. Antibiotic: Oregon Grape is a trusted antibiotic due to the berberine in its tissues. People have used berberine as a form of natural medicine in India and China for hundreds of years. Oregon grape is an attractive evergreen shrub that is native to the west coast of North America. Some evidence suggests that Oregon grape reduces the severity of symptoms associated with psoriasis and atopic dermatitis. Oregon grape root aka holly-leaf barberry is considered a bitter tonic and a natural antibacterial for dogs. Mahonia aquifolium, the Oregon grape, is a species of flowering plant in the family Berberidaceae, native to western North America. Caution: Contraindicated in pregnancy and lactation. For better Skin Conditions. Some herbalists have used these nutritional supplements for yeast and fungal infections, showing promising use in treating athletes foot. It's such a verdant green. This is something to be aware of in your search. Directions. Oregon grape root contains isoquinoline alkaloids, particularly berberine. It might be useful as a medical treatment once more information has been discovered about its action in our bodies. It's also very important that you check with your doctor if you have a serious pre-existing illness to see if he or she considers berberine to be safe for you. Growing to 1 m in height and 1.5 m in width, oregon grape pinnate leaves consist of spiny leaflets and dense clusters of yellow flowers in early spring. Drugs, supplements, and natural remedies may have dangerous side effects. Some plant chemicals can be dangerous inside the body. Suggested Use. [2, 7] For centuries, traditional Chinese healers have used berberine for a variety of health conditions, mainly inflammation and digestive woes. Mahonia aquifolium is native to western North America from British Columbia to California and eastward to Idaho and Montana. These berberine-containing plants have been used throughout the world dating back over 3,000 years. However, it is one of several plants high in berberine, which is responsible for it’s potent anti-microbial action. The alkaloid berberine is concentrated primarily in the roots, but if you’ve ever peeled away the bark of an Oregon grape or scratched off the surface of a twig, you’ll see the bright yellow berberine. Some berries should be left on the plant so that reproduction can occur. The Oregon Grape is carefully tested and produced to superior quality standards. It may also be transferred to the baby when he or she nurses. It is somewhat misnamed, as the fruit are not actually grapes. However, it is one of several plants high in berberine, which is responsible for it’s potent anti-microbial action. It’s used mainly to treat diarrhea and parasitic infections caused by bacteria (5). Berberine might have some health benefits. Use only as directed. Oregon Grape is anti-inflammatory and antibacterial – it is the first herb that I turn to when those lymph nodes below my ears become swollen and tender. This plant is native to western North America. You should ask your doctor's advice before using the substance. Berberine has been shown to exhibit activity in maintaining healthy intestinal flora. It is not related to grape; however, the name "Oregon grape" originated from its purple clusters of berries that resemble grapes. While berberine certainly exhibits antimicrobial activity, it’s important to understand that Oregon Grape is not a natural antibiotic. I know that sounds intimidating. Its alkaloid berberine is considered a moderate toxin with a human LD 50 of 27.5 mg/kg. Basically, what this means is that it works to decrease bacterial resistance to antibiotics. The berberine in Oregon grape can cause brain damage (kernicterus) in newborns, particularly premature newborns who have jaundice. Researchers have found that berberine is quickly "pumped" from some bacteria after it enters them, so it never gets a chance to kill the bacteria. I appreciate them both! In others, it seems to need the help of another substance in order to be effective. Berberine is a yellow alkaloid found in a variety of plants in addition to Oregon grape. In addition, berberine is present in the barberry, which is found in many countries, and in the Amur cork tree (or Amur corktree), which is native to Asia. 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